Dihydromyricetin (DHM), also known as ampelopsin, is a flavonoid compound extracted from Hovenia dulcis, commonly known as the Japanese raisin tree. DHM demonstrates a strong ability to lower blood alcohol levels when taken before alcohol consumption. As a potent antioxidant, Dihydromyricetin bulk helps the liver by clearing free radicals generated during alcohol metabolism. By accelerating alcohol clearance and providing hepatic protection, it can promote faster recovery from alcohol intoxication.
The bioactive compounds in Teng Cha include flavonoids like dihydromyricetin, myricetin, quercetin, and taxifolin; amino acids; vitamins; proteins; and essential trace elements.
Key properties of dihydromyricetin (DHM), a major flavonoid in Teng Cha:
Solubility - Dihydromyricetin bulk powder is easily soluble in hot water, ethanol, and acetone. It is also soluble in methanol and ethanol, slightly soluble in acetic ether, and insoluble in chloroform and petroleum ether.
Stability - DHM is stable under heat, but may become irreversibly oxidized when heated above 100°C. It is stable in acidic and neutral solutions. Aqueous DMY solutions may change slightly when heated over 80°C.
Taste - DHM has a mildly bitter taste that only minimally affects flavor. De-bittered DMY is available for specialized formulations requiring no bitterness.
Items | Standards | Results |
Physical Analysis | ||
Appearance | Fine Powder | Conforms |
Color | White Powder | Conforms |
Odor | Characteristic | Conforms |
Mesh Size | 100% through 80 mesh size | Conforms |
General Analysis | ||
Identification | Identical to R.S. sample | Conforms |
Dihydromyricetin | ≥98% | 98.32% |
Extract Solvents | Water and Ethanol | Conforms |
Loss on Drying (g/100g) | ≤5.0 | 3.04% |
Ash(g/100g) | ≤5.0 | 2.15% |
Chemical Analysis | ||
Pesticides Residue (mg/kg) | <0.05% | Conforms |
Residual Solvent | <0.05% | Conforms |
Residual Radiation | Negative | Conforms |
Lead(Pb) (mg/kg) | <3.0 | Conforms |
Arsenic(As) (mg/kg) | <2.0 | Conforms |
Cadmium(Cd) (mg/kg) | <1.0 | Conforms |
Mercury(Hg) (mg/kg) | <0.1 | Conforms |
Microbiological Analysis | ||
Total Plate Count(cfu/g) | ≤1,000 | 125 |
Molds and Yeast (cfu/g) | ≤100 | 18 |
Coliforms (cfu/g) | Negative | Conforms |
Salmonella(/25g) | Negative | Conforms |
As a cancer prevention agent, dihydromyricetin bulk can assist with killing free extremists that make oxidative harm cells. Enhancing with DHM might upgrade cell reinforcement limit and safeguard against age-related constant sicknesses.
Studies show DHM strongly inhibits inflammatory cytokines involved in cancer, autoimmunity, cardiovascular disease and more. DHM’s ability to suppress inflammation could have therapeutic potential for various conditions.
Research finds DHM can boost exercise performance by improving mitochondrial function and energy production in muscle cells. This enhances aerobic capacity and endurance, especially for high-intensity athletic activities.
Wholesale dihydromyricetin powder has gained popularity as a supplement to mitigate hangovers. It speeds up alcohol metabolism, preventing buildup of toxic byproducts like acetaldehyde linked to hangover symptoms. DHM also protects the liver from alcohol-induced injury.
The antioxidant properties of dihydromyricetin bulk powder may promote neuroprotective effects. Studies show DHM can reduce anxiety, stress and depression by optimizing levels of the calming neurotransmitter GABA in the brain.
Emerging evidence suggests DHM may help reduce drug-induced liver damage and lower fat accumulation in non-alcoholic fatty liver disease. More research is needed to confirm DHM’s hepatoprotective effects.
DHM appears to stimulate the hippocampus region of the brain, which is integral for memory and learning. Early studies show it can improve cognitive abilities like memory formation, boosting mental acuity.
By facilitating GABA signaling, DHM has a calming effect that can improve sleep quality and duration. This also helps relax muscular tension that interferes with restful sleep.
Here are some examples of the application of dihydromyricetin (DHM) in functional foods, medicines, and cosmetics based on current research:
Functional Foods:
A randomized trial found that consuming a yogurt drink with 10mg/mL DHM increased plasma antioxidant capacity in humans. This indicates DHM's potential as an antioxidant additive.
Animal studies show fortifying foods/beverages with dihydromyricetin bulk powder can protect the liver from alcohol-induced fatty buildup and injury. DHM-infused alcohol beverages could help mitigate hangovers.
DHM's anti-inflammatory properties may make it suitable for functional foods targeting conditions like arthritis, atherosclerosis, and autoimmune disorders, though more research is needed.
Medicines:
A meta-analysis of 7 trials found DHM supplements at doses of 200-600mg per day significantly improved memory and cognitive function compared to placebo. DHM shows potential against age-related cognitive decline.
DHM's mood-enhancing effects are being explored for antidepressant potential. One study showed co-administering DHM with an SSRI enhanced antidepressant efficacy in rats.
DHM is being investigated as an adjuvant treatment for certain liver conditions. A trial in humans found DHM improved antioxidant status in patients with hepatitis B.
Cosmetics:
Skin creams with 0.1-0.3% DHM have been shown to reduce skin redness, wrinkles, and sunburn severity in animal models, owing to DHM's antioxidant effects.
In hair products, DHM could help combat oxidative stress that damages hair follicles. One study found a DHM shampoo reduced hair loss in women.
An eye drop solution containing 0.2% DHM was found to effectively treat ocular oxidation and prevent cataracts in diabetic rat models.
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